Nasal spray desmopressin acetate rx only description ddavp nasal spray desmopressin acetate is a synthetic analogue of the natural pituitary hormone 8arginine vasopressin adh, an antidiuretic hormone affecting renal water conservation. It contains the active ingredient desmopressin acetate dissolved in water for injection. Discover the latest products from american health packaging. Ddavp injection 4 mcgml contains as active substance, desmopressin acetate, a. The advantage of the melt form is that it is not affected by food in the stomach. Product monograph prddavp tablets desmopressin acetate 0.
It consists of a clear, colourless liquid containing 0. Sandostatin may alter absorption of dietary fats in some patients. The exact fraction of drug absorbed by that route of administration has not been quantitatively determined. One ml 4 mcg of desmopressin acetate solution has an antidiuretic activity of about 16 iu.
Ddavp is contraindicated in patients with moderate to severe renal impairment defined as a creatinine clearance below 50mlmin. In an mh crisis, contact the 24hour mhaus hotline at 800. Desmopressin spray should only be used by the nasal route. Infed iron dextran injection usp is a dark brown, slightly viscous sterile liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. Product monograph template standard ferring canada. Supporting documents older than three years hespan 6% hetastarch in 0. Ddavp injection 4 mcgml is provided as a sterile, aqueous solution for injection. Desmopressin acetate is mainly excreted in the urine. See what pharmaceuticals, medications and treatments are now available in our hospital unit dose, unit dose plus and liquid unit does lines. While holding onto the diluent vial, carefully remove the outer package from the mix2vial, being careful to leave the mix2vial attached firmly to the diluent vial fig.
Desmopressin is a manmade form of vasopressin and is used to replace a low level of vasopressin. Injection desmopressin acetate 4 mcgml rx only description ddavp injection desmopressin acetate 4 mcgml is a synthetic analogue of the natural pituitary hormone 8arginine vasopressin adh, an antidiuretic hormone affecting renal water conservation. Package insert template for metformin tablet brand or product. Sep 01, 2019 ddavp is contraindicated in patients with hyponatremia or a history of hyponatremia. Ddavp nasal spray should only be used in patients where orally administered. Desmopressin free base represents approximately 89% of the.
Desmopressin acetate injection desmopressin acetate 4 mcgml is a synthetic analogue of the natural pituitary hormone 8arginine vasopressin adh, an antidiuretic hormone. The time to reach maximum plasma desmopressin acetate levels ranged from 0. This leaflet is part iii of a threepart product monograph. Store reconstituted suspensions at controlled room temperature. Ddavpdesmopressin injection is a clear, sterile aqueous solution. This medication helps to control increased thirst and too much urination due to these conditions. Desmopressin is a synthetic replacement version of the natural hormone vasopressin. Desmopressin is the most popular medicine used to treat bedwetting. Do not drink anything until the next morning, or at least 8 hours after you have taken the medicine. Feb 28, 2017 desmopressin is the most popular medicine used to treat bedwetting.
Dec 01, 2019 the bioavailability of desmopressin acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0. Imitrex nasal spray is contraindicated in patients with a history of stroke or tia. Ddavp injection desmopressin acetate injection 4 mcgml is available as a sterile solution in cartons of ten 1 ml singledose ampules ndc 0075245101 and in 10 ml multipledose. Csl behring stimate desmopressin acetate nasal spray, 1. The exact fraction of drug absorbed by that route of administration has not. Csl behring llc stimate package insert desmopressin acetate revised. The product catalog provides you with a full listing of tevas brand and generic product lines. Initiation of treatment in patients over 65 years of age is not. Precedex is supplied as a clear, colorless, isotonic solution with a ph of 4.
Management view in chinese with oral desmopressin, it is recommended that fluid intake. The name of your medicine is desmopressin spray, 10 microgramsdose, nasal spray, solution referred to as desmopressin spray throughout this leaflet. The australian product information pi for minirin tablets and melt state that. Desmopressin acetate nasal spray june 3, 2003 edited sept. Octostim desmopressin acetate treatment without concomitant restriction of. While treating nighttime bedwetting, avoid drinking anything within 1 hour before your bedtime dose of desmopressin. Ddavp intranasal spray, after one week of selftitration from spray to tablets, patients diuresis was controlled with 0. Sandostatin also suppresses secretion of thyroid stimulating hormone, which may result in hypothyroidism. Desmopressin spray 10 microgramsdose nasal spray solution. Highlights of prescribing information these highlights do not. Ddavp desmopressin injection is a clear, sterile aqueous solution. Desmopressin free base represents approximately 89% of the desmopressin acetate content. Desmopressin acetate will also stop bleeding in patients with hemophilia a with episodes of. Desmopressin ddavp and stimate side effects, dosage.
A hyponatremia or a history of uncorrected hyponatremia, b. Store reconstituted suspensions at controlled room temperature 68f to 77f or 20c to 25c. List of drug approvals by the medicines control council in south africa containing desmopressin acetate on. Restasis should not be administered while wearing contact lenses. Ddavp is a potent antidiuretic which, when administered, may lead to water intoxication andor hyponatremia. Management view in chinese with oral desmopressin, it is recommended that fluid intake be limited to eight ounces 240 ml from one hour before to eight hours after administration of desmopressin. Antihemophilic factorvon willebrand factor complex human, humatep is approved to treat and prevent bleeding in adult patients with hemophilia a classical hemophilia.
Risk factors for metformin associated lactic acidosis include renal impairment, concomitant use of certain drugs e. Please read this information leaflet carefully before treatment with the. These highlights do not include all the information needed to use. The 10 ml vial contains chlorobutanol as a preservative 5 mgml. What should i avoid while taking desmopressin ddavp, nocdurna. A pharmacokinetic study conducted in healthy volunteers and patients with mild, moderate, and severe. Ddavp rhinal tube desmopressin acetate rx only description ddavp rhinal tube desmopressin acetate is a synthetic analogue of the natural pituitary hormone 8arginine vasopressin adh, an antidiuretic hormone affecting renal water conservation. If the patient was previously receiving desmopressin injection, administer 10 times the amount of desmopressin acetate, rounding down to the nearest 10 mcg.
Hyponatremia see full prescribing information for complete boxed warning. Ddavp is contraindicated in patients with hyponatremia or a history of hyponatremia. Read this patient information leaflet before you start taking stimate nasal spray. While treating nighttime bedwetting, avoid drinking anything within 1 hour before your bedtime dose of. Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for ddavp desmopressin. Desmopressin tablets fda prescribing information, side. Australian public assessment report for desmopressin tga. Ddavp injection desmopressin acetate 4 mcgml is a synthetic analogue of the. Csl behring llc stimate package insert desmopressin. Ddavp fda prescribing information, side effects and uses. Each ml contains the equivalent of 50 mg of elemental iron as an iron dextran complex, approximately 0. The bioavailability of desmopressin acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0. Push the blue plastic cannula of the mix2vial firmly through the rubber stopper of the diluent vial fig.
Lenses may be reinserted 15 minutes following administration of restasis ophthalmic emulsion. Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for ddavp desmopressin skip to. Desmopressin can also be used in patients with less severe di who do not want nocturnal enuresis in children. Sandostatin octreotide acetate alters the balance between the counterregulatory hormones, insulin, glucagon and growth hormone, which may result in hypoglycemia or hyperglycemia. Ddavp tablets should be used in conjunction with nonmedicinal therapy, such as motivational counselling and bladder exercises. Mar 01, 2018 product approval information is indicated for. Ddavp tablets desmopressin acetate dose, indications. The solution also contains the inactive ingredients sodium chloride to adjust the concentration and hydrochloric acid to adjust the acidity of the solution to values which are suitable for.
Ddavp nasal spray desmopressin acetate is a synthetic analogue of the natural pituitary hormone 8arginine vasopressin adh, an antidiuretic hormone affecting renal water conservation. Avp and some of its analogs, such as porcine 8lysinevasopressin lvp and desmopressin 1deamino, 8d argininevasopressin, have been used in a number of clinical settings. For patients with multiple cardiovascular risk factors who have a negative cardiovascular evaluation, consider administering the first dose of imitrex nasal spray in a medically supervised setting and performing an electrocardiogram ecg immediately following administration of imitrex nasal spray. Each 1 ml of precedex contains 118 mcg of dexmedetomidine hcl equivalent to 100 mcg dexmedetomidine base and 9 mg of sodium chloride in water. The catalog displays all strengths and sizes along with the description, imprint code, ndc and photo for each product. Patients with decreased tear production typically should not wear contact lenses. It works by reducing urine production in the kidneys. Push the blue plastic cannula of the mix2vial firmly through the rubber stopper of the diluent. Very rare cases of hyponatremia have been reported from worldwide postmarketing experience in patients treated with ddavp desmopressin acetate.
White, round, sublingual wafer marked with two drop shaped figures on one side. Control and prevention of bleeding in patients with hemophilia a or acquired factor viii fviii deficiency 1. The catalog displays all strengths and sizes along with the description, imprint code, ndc and photo for each. Drug name availability desmopressin sublingual tablet nocdurna sublingual tablets. Mar 09, 2020 desmopressin acetate injection 4 mcgml contains as active substance, desmopressin acetate, a synthetic analogue of the natural hormone arginine vasopressin. A pharmacokinetic study conducted in healthy volunteers and patients with mild, moderate, and severe renal impairment n24, 6 subjects in each group receiving single dose desmopressin acetate 2 mcg injection demonstrated a difference in desmopressin acetate terminal halflife. Ddavp desmopressin acetate tablets side effects, images. White, round, sublingual wafer marked with three drop shaped figures on one side. In patients with severe renal failure requiring dialysis, the halflife of sandostatin may be increased, necessitating adjustment of the. Clinical pharmacology ddavp tablets contain as active substance, desmopressin acetate, a synthetic analogue of the natural hormone arginine vasopressin. Product information for auspar glypressin ferring pharmaceuticals pty ltd pm20100318233 final 26 november 2012. Jun 27, 2017 what should i avoid while taking desmopressin ddavp, nocdurna.
Ddavp and stimate are not indicated for the treatment of hemophilia a with. If contact lenses are worn, they should be removed prior to the administration of the emulsion. If the patient was previously receiving desmopressin tablets, dose titration is required because intranasal desmopressin is approximately 10 to 40 fold more potent than oral tablet. A melt tablet which is put under the tongue to dissolve and go straight into the bloodstream.
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